News

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qPCR kits released!

April 25, 2017

The Non-T and Non-B Genomic Detection kits are now available for quantitative PCR (real-time PCR) instruments. In addition, we are pleased to introduce the brand new qPCR Non-Myeloid Genomic Detection kit, designed to assess the purity of Myeloid cell preparations directly at the DNA level.

New Publication

January 2015

British Journal of Haematology, 2015, 168, 26–37
Monitoring of chimerism following allogeneic haematopoietic stem cell transplantation (HSCT): technical recommendations for the use of short tandem repeat (STR) based techniques, on behalf of the United Kingdom National External Quality Assessment Service for Leucocyte Immunophenotyping Chimerism Working Group.

New Publication

October 31, 2014

Congratulations to Lebedeva et al. for the publication of their poster from the 2014 ASHI Annual Meeting "ASSESSMENT OF CELL FRACTION PURITY BY PCR ON SEQUENTIAL LINEGE-SPECIFIC CELL SEPARATIONS FOR CHIMERISM MONITORING" in Human Immunology, Volume 75, Supplement, page 103 (2014). This article features Accumol's Non-T and Non-B Genomic Detection Kits.

New! MTBN Purity Assessment Kit

January 9, 2014

We are happy to announce the release of the MTBN Purity Assessment Kit. This kit is designed to assess the purity of Myeloid cells (CD15, CD33, CD66b, CD14), as well as T- and B-cells. In addition, it can be used to measure contaminating lymphoid or Myeloid cells in any cell preparation.

New Publication

September 17, 2013

Congratulations to Hanson et al. for the publication of their article "Assessment of the purity of isolated cell populations for lineage-specific chimerism monitoring post haematopoietic stem cell transplantation." in Tissue Antigens, Volume 82, Issue 4, pages 269–275 (2013). This article features Accumol's Non-T and Non-B Genomic Detection Kits, and discusses the importance of purity control following cell isolation.

New PDF for download

January 28, 2013

The Non-T and Non-B Genomic Detection Kits Documentation has been updated. Shelf life is now 1 year from the manufacturing date.

New kit sizes

July 14, 2012

The Non-T and Non-B Genomic Detection Kits are now available in two sizes: 32 and 96 reactions.

Free sample offer

January 15, 2012

For a limited time, Accumol will offer free samples of the Non-T and Non-B Genomic Detection Kits to new customers. Please use the contact form to order your sample today.

Coming Soon

January 02, 2012

Accumol's Non-B Genomic Detection Kit will allow the detection of Non-B Cell DNA in genomic DNA samples prepared from sorted B Cells. We expect the kit to be ready for release within the next few weeks.

New product release

December 15, 2012

Accumol is delighted to announce the launch of their first kit, the Non-T Genomic Detection Kit. Accumol's Non-T Genomic Detection Kit can accurately measure the purity of sorted T-Cells (CD3+ lymphocytes), directly on a DNA sample isolated from these cells.

Accumol's website is up and running!

December 01, 2011

Welcome to Accumol's website. We hope you'll find it useful and informative. This site will grow and improve over time. Visit it often to stay informed of new products, documentations, upcoming meetings... or subscribe to our emailing list, and we will inform you of any significant addition to this site.

Change in EFI and ASHI Regulations

October 01, 2011

Chimerism analysis labs are now able to apply for EFI (European Federation for Immunogenetics) accreditation. The new guidelines, effective October 1, 2011, specify that "When HCE (Haemopoietic Chimaerism and Engraftment) testing is performed on cellular subsets isolated by cell sorting, the purity of the sorted population must be documented and taken into account in the analysis of the results."

This is similar to the ASHI (American Society for Histocompatibility and Immunogenetics) 2011 standards, which require that chimerism labs "Document the purity obtained if processing involves isolation of cell subsets."

*EFI Standards 2011, Section I4.190:

"When HCE (Haemopoietic Chimaerism and Engraftment) testing is performed on cellular subsets isolated by cell sorting, the purity of the sorted population must be documented and taken into account in the analysis of the results. If this is not possible it must be clearly stated in the report."

ASHI Guidelines 2011, Section D.5.3.4.1.8:

"Document the purity obtained if processing involves isolation of cell subsets. If purity is not assessed, this must be documented on the test report."

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Mailing Address:
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Alastair Ross Technology Centre
Calgary, Alberta, T2L 2K7
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orders@accumol.com

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